CHEM 2414 Basic Organic and Biochemistry Lec

CHEM 2414 Basic Organic and Biochemistry Lec. 4 Lab. 0 Cr. 4

Fall 2005 Section: [21] Time/Day: 4:00-7:50 p.m. T Room: SCI 218

Instructor: Mr. John Taylor

Instructor’s Office: Science 215 Office Phone: (318) 427- 44357

Cell Phone: (813) 361-4379 (Monday, Fridays and weekends)

Email: jtaylor@lsua.edu alternate jtaylor@lsua.info

MAPS Division Office: 473-6591

Text:

General, Organic, and Biochemistry

Katherine J Denniston, TOWSON UNIVERSITY
Joseph J Topping, TOWSON UNIVERSITY
Robert L Caret, SAN JOSE STATE UNIV

Hardcover, 896 pages

Dennison, Topping, Caret

4^th Edition;

Course Description

(Also offered as BIOL 2414). Prerequisite: CHEM 1202. A presentation of:

1) the fundamental reaction capabilities of organic molecules and their functional groups, and

2) the basic principles of physiological chemistry with an emphasis on their application to problems encountered in the practice of nursing.

Four hours of lecture each week.

Table of Contents

General Chemistry (assumed prerequisite)

1 Chemistry: Methods and Measurement

2 The Composition and Structure of the Atom

3 Elements, Atoms, Ions, and the Periodic Table

4 Structure and Properties of Ionic and Covalent Compounds

5 Calculations and the Chemical Equation

6 States of Matter: Gases, Liquids, and Solids

7 Reactions and Solutions

8 Chemical and Physical Change: Energy, Rate, and Equilibrium

9 Charge-Transfer Reactions: Acids and Bases and Oxidation-Reduction

10 The Nucleus, Radioactivity, and Nuclear Medicine

Organic Chemistry (all chapters covered)

11 An Introduction to Organic Chemistry: The Saturated Hydrocarbons

12 The Unsaturated Hydrocarbons: Alkenes, Alkynes, and Aromatics

13 Alcohols, Phenols, Thiols, and Ethers

14 Aldehydes and Ketones

15 Carboxylic Acids and Carboxylic Acid Derivatives

16 Amines and Amides

Biochemistry (all chapters covered)

17 Carbohydrates

18 Lipids and Their Functions in Biochemical Systems

19 Protein Structure and Function

20 Enzymes

21 Carbohydrate Metabolism

22 Aerobic Respiration and Energy Production

23 Fatty Acid Metabolism

24 Introduction to Molecular Genetics

Appendixes

A A Review of Mathematics Applied to Problem Solving in Chemistry

B Table of Formula Weights

C Determination of Composition and Formulas of Compounds

D Stereochemistry and Stereoisomers Revisited

E Lipid-Soluble Vitamins

F Water-Soluble Vitamins

G Energy Yields from Aerobic Respiration: Some Alternatives

H Minerals and Cellular Function

Course Objectives

Students will:

1. Understand the implications of structure and functional groups on reactivity, physical behavior and chemical behavior of organic molecules.

2. Identify the typical uses of the various classes of molecules.

3. Understand the outcome of reactions of the various functional groups.

4. Understand the principles of stereochemistry and their application to reactivity and biological behavior.

5. Be able to properly name organic molecules and draw structures from a name.

6. Recognize biomolecules and reactions typical for them.

7. Understand the various roles of biological molecules in living systems.

8. Understand metabolism and regulation of metabolism.

Detailed Topical Outline

0. Review of Chemical Bonding, Molecular Geometry, Acids & Bases, pH

1. Carbon chains, bonding, and model building

2. Functional groups: nomenclature, physical and chemical properties, reactions.

a. Saturated hydrocarbons

b. Unsaturated hydrocarbons and aromatics

c. Alcohols, phenols, thiols and ethers

d. Aldehydes and ketones

e. Carboxylic acids and derivatives

f. Amines and amides

3. Biomolecules: Structure and Function

a. Carbohydrates

b. Lipids

c. Amino acids and proteins

d. Enzymes

e. Bases, nucleotides, RNA and DNA

4. Metabolism

a. Carbohydrates

b. Aerobic respiration and energy

c. Lipid catabolism

d. Amino acid catabolism

5. An introduction to molecular genetics

a. Replication

b. Transcription

c. Translation

This synthesis of this molecule changed Organic Chemistry:

Do you know the story?

ATTENDANCE:

Students are expected to attend class and will be responsible for all material presented. Pretest quizzes will be administered during every class which is not a scheduled exam day. These quizzes may not be made up outside of class time.

MAKE-UP POLICY:

Make-up exams are usually not given. In the event of an unavoidable absence (jury duty, hospitalization, incarceration, and death in the immediate family), you must contact the instructor, no later than, the day of the exam in order to discuss what arrangements might be made. A message must be left on the instructor's e-mail (jtaylor@lsua.edu) if the instructor cannot be reached. If a makeup is allowed, it must be completed prior to return of the exam papers completed by the student attending. Missed exams will otherwise count as 0 points. Student who takes the test on the assigned test day are guaranteed to receive their graded exam on or before the next exam day after completion of the new exam, otherwise the student will be assigned a 100% grade for the un-graded paper.

GRADING:

Exams mainly determine a student's letter grade. There will be 1000 points possible in the course. The four hourly exams are worth 100-200 points each. The final exam is worth 200 points. Homework will not exceed 15% of the grade. The approximate grade distribution is:

900 - 1000 points = A
800 -   899 points = B
700 -   799 points = C
600 -   699 points = D
The instructor reserves the right to make necessary modifications or adjustments to the point structure above during the semester as necessary, except the grade level will not change from 90%, 80%, 70% etc. of the total points.

Exams (Approximate Date):

Exam 1 (T, Sept 13): Chapters. Chapter 11, 12

Exam 2 (T, Oct 4): Chapters 13, 14, 15, 16

Exam 3 (T, Nov 1): Chapters 17, 18, 19, 20

Exam 4 (T, Nov 29): Chapters 21, 22, 23, 24

Final Exam (T, Dec 6, 4:00-7:00 p.m.): All topics-Multiple Choice

Exams will be based on material covered in the lecture as well as additional reading assignments outlined on the course calendar.

Daily Quizzes (optional):

Scored pretest quizzes are NOT recorded in the instructor’s grade book, but must be attached to the Exam the day of the exam to receive the pretest grade. The scores may be recorded on the attendance sheet. The instructor only records Module Exam totals and the Final Exam in his grade book. The pretests may NOT be used during the exam! Samples of each section (pretest) of each exam may be found on the grading outline on the web site after the first two weeks of class.

Link to: Chem 2414 Grading Outline

WEB-SITE:

This course uses the Desire2learn web site giving you access to course information, Email, and check-your-grade through the Internet. Access the web site at: http://lsua.edu. Your username is your first, middle and last initial (all in caps) followed by the last 4 digits of your student ID number. Your password is your student identification number.

OFFICIAL OFFICE HOURS:
(see posting on the instructor’s door for changes and postponements)
Monday: 4:00-6:00 p.m.

Tuesday: 12:30-1:00; 2:15-2:45; 3:30-4:00 p.m.

Wednesday: 3:00-4:00; 5:00-6:00 p.m.

Thursday: 12:30-1:00; 2:15-3:45; 4:30-6:00 p.m.

Friday: 8:30-9:30 a.m.

(Unofficial – anytime I am in my office)

Instructor’s Right to Change or Modify Grading Procedures:

This instructor reserves the right to make changes in this syllabus whenever he feels it is appropriate to do so. The instructor reserves the right to modify or change the grading progress as the course proceeds. Any additional course assignments will substitute for deleted items. Some may also be modified if not deleted. The instructor will not add major examinations as a modification and maintain the four exam plus final requirements

Students with Disabilities:

Qualified students with documented disabilities are eligible for physical and academic accommodations under the American Disabilities Act and Section 504 of the Rehabilitation Act of 1973. Students requesting accommodations should contact this professor during the first week of class with official documentation of disability

Withdrawal Policy:

Students will be allowed to withdraw from this class any time during the semester through Tuesay, November 1, 2005 and will receive a grade of “W”. After this date a letter grade will be assigned reflecting the student’s performance in the class. Students failing to attend class for two consecutive weeks are subject to withdrawal by the instructor according to LSUA policy.

Academic Misconduct:

Academic misconduct or dishonesty such as cheating and plagiarism is not permitted. Suspected cases may be reported to the LSUA administration and may result in failure of an assignment or exclusion from the class. Also, the instructor reserves the right to reassign work to students if the instructor senses/suspects the work submitted is not the work of the student. (No questions asked-The instructor may tell the student to reattempt the work to earn the daily quiz grade or examination grade or the instructor may assign a zero if second request is made).

Classroom Etiquette:

Students are expected to conduct themselves as adults in the classroom showing respect to their classmates. Only persons registered for this class are permitted in the classroom. As a courtesy to the instructor and your fellow classmates, cellular telephones and pagers should be cut off before entering the classroom or laboratory. Likewise, the instructor sometimes forgets to shut his down at the beginning of class, so hopefully someone sitting close to the front may remind the instructor with a hand gesture for him to check his phone,

Studying:

Chemistry is a cumulative subject. Concepts learned in the first assigned chapter will be applied in the second, etc. The final exam is cumulative. In order to do well in this course, it is essential to study and work problems. The following is a list of study suggestions

1) Read the text chapters before the material is covered in class.

2) Take good notes and review them daily.

3) Work all assigned homework problems at the end of the assigned chapters. Do not get behind!!!!!!

4) Work the practice exams that are available on the web site without looking at the answer key.

5) Use the interactive web site for studying.

Procedures to Evaluate these Objectives

1. In-class and homework problems after concept presentation

2. In class e-presentation system responses

3. In-class exams with pretests

4. Cumulative final exam

Instructor Requested Information:

During the first week of class, the student will fill out a 4x6 file card. The instructor has provided a sample below with his personal data and his block scheduled time. The completion of this card is worth (2 points) toward the student's final grade

Data Card (4x6 file card): Front Side (Personal Data)

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Name: John Taylor CHEM 1001

Office: Science 215

Address: 6956 England Drive

Alexandria, LA 71303

Telephone: 427-4435 (office) 445-9894 (home till 9/30)

Cell: 813 361-4379 (cell after 9pm Tues-Fri- all day Mon & weekends)

E-MAIL : jtaylor@lsua.edu or jtaylor@hccfl.edu

Employment: LSU-Alexandria since 8/15/05

Full time chemistry faculty

Major: Instructional Technologies Minor: Chemical Education

Long Term Goal: Educational Software Developer

Prerequisite: CHEM 1202 completed Final grade: A

Software/Computer Literacy: WP: Word

Home Computer: yes Internet ISP: yes or have access

Why are you taking this course?

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